You have screened a fragment library against your target protein. You suspect that one of your hits may have entropicall
Posted: Tue May 17, 2022 8:41 am
You have screened a fragment library against your target protein. You suspect that one of your hits may have entropically driven binding. Which method should you use to measure the entropic contribution of fragment binding? O A. X-ray Crystallography B. Surface Plasmon Resonance (SPR) C. 1H-Nuclear Magnetic Resonance (1H-NMR) D. Isothermal Calorimetry (ITC) O E. Thermal Shift Assay