Provide a detailed mechanism to account for the acid-catalyzed cyclization of the alcohol 1 to give the tricyclic acetal
Posted: Tue May 17, 2022 8:22 am
Provide a detailed mechanism to account for the acid-catalyzed cyclization of the alcohol 1 to give the tricyclic acetal 2. Show the curly arrows for each bond-forming and bond-breaking step. Show the structure of each intermediate, charged or neutral, in your mechanism. (You only need to show one reasonable resonance contributor for each intermediate.) H2SO4 (cat.) HO CH2OH Meo 1 2