08:34 Done MAIN_2022_4LM... ☆ xa Question 3 Suspension formulations are an attractive formulation to be administered via
Posted: Mon May 16, 2022 10:26 pm
08:34 Done MAIN_2022_4LM... ☆ xa Question 3 Suspension formulations are an attractive formulation to be administered via the oral route but suffer from several instabilities. a) Discuss why suspensions may be an advantageous dosage form for oral administration (20 % marks) b) Describe the processes of caking and flocculation and explain why these instabilities may occur in a suspension using DLVO theory [80% marks] Question 4 a) Draw and the following structures showing any lone pair electrons and assign any formal charges to the atoms. (20% of marks) нно H H-C H H-N -N-C-C HH O-H H b) Identify the functional groups in aspirin and paracetamol. Explain, with reference to the functional groups involved and resonance forms, why aspirin acts as an acid and is mostly lonised in water, whereas paracetamol is mostly non-ionised. (80% marks) O NH بين тон OH aspirin paracetamol Page 3 of 4 4LMS0213 Drugs and Medicines o Reply... E