Answer Happy

(1) Match each molecule or class of molecules to the description of its biochemical role or physiological effect (2 pts each correct match) (Class of) Molecule(s) Description 1. Arginine A. Intermediate in the tri-carboxylic acid cycle whose production is catalyzed by the iron-sulfur cluster containing enzyme aconitase 2. Citrate B. Proteinogenic amino acid that also plays a key role in the urca cycle 3. Dihydroxyacetone Phosphate C. Nucleobase found in RNA but not DNA, in part due to its tendency to tautomerize 4. Fructose-2.6-bisphosphate D. Intermediate in the tri-carboxylic acid cycle as well as in gluconeogenesis; in the latter pathway, it is produced by biotin dependent carboxylation of pyruvate 5. Furanose E. Intermediate in glycolysis converted to glyceraldehyde-3-phosphate via an enediol intermediate 6. Isocitrate F. Accumulation of this molecule causes extremely rapid activation of PFK-1 (and inactivation of FbPase-1) leading to activation of glycolysis and inactivation of gluconeogenesis 7. Oxaloacetate G. Adaptor molecule that translates the genetic code as well as serves as the leaving group in peptide bond formation 8. RNA H. Form of a monosaccharide with a 5 membered ring 9. Uracil I. Intermediate in the tri-carboxylic acid cycle that also carries activated acetate units into the cytoplasm for lipid biosynthesis