Page 1 of 1
4. Explain how compound 10 is converted to 9 in scheme 2 (multiple steps, and what is a Piv group?). Scheme 2. Synthesis
Posted: Tue Nov 16, 2021 6:24 am
by answerhappygod
- 4 Explain How Compound 10 Is Converted To 9 In Scheme 2 Multiple Steps And What Is A Piv Group Scheme 2 Synthesis 1 (21.64 KiB) Viewed 37 times
4. Explain how compound 10 is converted to 9 in scheme 2 (multiple steps, and what is a Piv group?). Scheme 2. Synthesis of Cyclobutenecarboxylate (+)-9 OH Оме Br ref 16 OH Br K.co. Me,SO CHO DMF, OH 59% 13 CHO OH 12 CHO Омо 14 Оме BI Оме Br CH, CHMBI THF, -78 °C 98% NaHMDS, 15 THF. -78 °C 71% OM O OM OH (a)-10 O (1)-9 + pivaloyl ester (25%) HO Pivo EI.N. PICI THF, O'C 0 11 15