Which of the following statements is false (10 points) Small nucleophiles prefer to attack cyclohexanone carbonyl groups

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Which Of The Following Statements Is False 10 Points Small Nucleophiles Prefer To Attack Cyclohexanone Carbonyl Groups 1 (43.86 KiB) Viewed 36 times

Which of the following statements is false (10 points) Small nucleophiles prefer to attack cyclohexanone carbonyl groups from an axial approach so as to avoid torsional strain that would occur with attack from an equitorial direction Large nucleophiles prefer to attack cyclohexanone carbonyl groups from an equitorial direction so as to avoid clashes with axial substituents in an alternative axial approach Nucleophiles prefer to attack carbonyl groups at an angle of about 109 degrees so as to maximize overlap with the pi* orbital while minimizing interaction with the electron-rich pi orbital. Nucleophilic attack on functional groups in acyclic systems are typically more diastereoselective than attack on those within cyclic structures, 3 Which structure (structures) correspond to the predicted major diastereomer for the Grignard addition reaction shown? (10 Points) Et Mg BR _ ? me. OH Me ou to re HO (О. me me ne A B с D