8. Consider the following reaction which converts (R)-2-phenylpropanal to 4-phenyl-1- pentyn-3-ol H CH3 H CH3 OH 1. Nat
Posted: Mon Nov 15, 2021 4:54 pm
8. Consider the following reaction which converts (R)-2-phenylpropanal to 4-phenyl-1- pentyn-3-ol H CH3 H CH3 OH 1. Nat CECH 2. H30+ H нс CH (R)-2-Phenylpropanal 4-Phenyl-1-pentyn-3-ol a) Other than the aromatic ring, suggest two functional groups which is present in the product. (2 marks) b) Suggest the type of organic reaction. (1 mark) c) Suggest a method to prepare sodium acetylide (Nat C=CH). (1 mark) d) It is suggested that the product exhibits stereoisomerism. If (R)-2-Phenylpropanal is attacked in the Re face, draw the expected stereoisomer and assign R or S configuration. (2 marks) e) It is reported that the two products exhibit optical activity under polarized light. A student suggested that they are racemic mixture which result in no optical activity. Criticize the opinion. (2 marks) f) Using the concept from the above reaction, suggest and describe a method to separate the racemic mixture of butan-2-amine. (4 marks)