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Study Participant Total Person Years EEEEEEEE ======== ======= EESEEX EEEEEEEE EEEEEEEE EEEEEEEE EEEEEEEE ======== ======== ======== ======== =======D =D EEEEEEEE EEEEEEEE EESEEEEE EEEEEEEE 1 2 3 4 4 5 Years X= Death EEEEEEE ======== SESSESES EEEEEEEE =======L EEEEEEE EEEEEEEE 3 3 ======== 5 ======== 6 EEEEEEEE 7 ===== 8 4 1 2 D=Disease L=Loss to follow up 4. Fill in the total Person Years contributed in the last column (white) of table above. 5. What is the total person-time contributed by all participants in total? Please show all work. 6. Over the 8 years for this study population, what is the person-time incidence rate of disease (D)? Show all work and express it as per 100 person years. 7. A local community experienced an outbreak of Shigellosis. 18 residents from 18 different households were affected. The local population of their community was 1,000. Calculate the primary Attack Rate of shigellosis for this community and show all work. One incubation period later, 17 persons in the same households as these 'primary' cases developed shigellosis. If the 18 households included 86 persons, calculate the secondary attack rate and show all work and express as a %.

Date of onset of illness + Date of death Date of recovery Person # 1 + 2 3 4 5 3 In a hospital ward population of 20 people, there were 10 new cases of Tuberculosis (TB) in between October 1, 2004, and Sept. 30th, 2005. Each horizontal line represents one of the 10 cases. Keep in mind that the entire population is 20 people, however, only the 10 cases of TB are shown in the below chart. The down arrow indicates the date of onset of illness. The solid line represents the duration of illness. The up arrow and the cross represent the date of recovery and date of death, respectively. Using this information, answer Q 1-3 6 7 85 9 3 10 Oct. 1. 2004 Apr. 1, 2005 Sept. 30, 2005 1. Calculate the incidence rate from October 1, 2004, to September 30, 2005, using the midpoint population (population alive on April 1, 2005) as the denominator. Express the rate as per 100 persons and show all work. 2. Point prevalence is the number of persons ill on the date divided by the population on that date. How many persons were ill on April 1st? Calculate the point prevalence on April 1, 2005 and show all work (remember to x by 100 to get %). 3. Calculate the period prevalence from October 1, 2004, to April 1, 2005. The numerator of period prevalence includes anyone who was ill any time during the period and denominator is entire population. Show all work (remember to x by 100 to get %).

Study Participant Total Person Years 1 ======== ======== ======= EX 2 ======== ======== ======== ======== ======== ======== ======== 3 ======== ======== ======== ======== =======D 4 ======== ======== ======== ======== ======= ======== ======== ======== ======== ======== ======== 5 Years X= Death 3 4 5 7 8 1 2 D=Disease L=Loss to follow up