Bite of Anopheles mosquito Skin Lymph node Sporozoites 35 yrys Lymphatic B cell رک The cell Th cell MHC Antibodies MHCI
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Bite of Anopheles mosquito Skin Lymph node Sporozoites 35 yrys Lymphatic B cell رک The cell Th cell MHC Antibodies MHCI Te cell Liver FN-Y NK cell (cos. Tdell Küpffer cells Hepatocyte NO/ROS CDH Tell 3 Immune response against malaria pre-erythrocytic stages (sporozoites and liver stages). DC, dendritic cells; Th, CD4+ T- helper cells; Tc, CD8+ T-cytotoxic cells; MHC, major histompatibility complex; NK, natural killer cells; IFN-y. Interferon-gamma; NO, nitric oxide; ROI, reactive oxygen intermediates. (For colour version of this figure, the reader is referred to the online version of this book).