Answer Happy

The A allele of G6PD confers some protection against malaria. The frequency of A in western African populations is about 11%. If A is at equilibrium frequency, what is the selection coefficient against normal (BB) homozygotes if the individuals homozygous for A have a 50% chance of surviving to adulthood in western Africa? (Ignore the presence of other alleles.) (Give your answer to two decimal places.] Question 5 2 pts The fixation probability for a recessive advantageous mutant ( UM = 1, vaa = Vax = 1 - s ) in a population containing N individuals is 2s Νπ Notice that this probability depends on N no matter how large s is. The fixation probability of a strongly advantageous allele with an additive effect of 0.1% on viability is approximately 2s = 0.002. How large would s have to be for a recessive advantageous allele to have the same fixation probability in a population of 10,000 individuals? [Give your answer to three decimal places.)