SARS-CoV viral capsid protease enzyme cleaves its target peptide substrate with a Vmax of 275 mM min-1. The Km for its p
Posted: Mon May 09, 2022 3:19 pm
SARS-CoV viral capsid protease enzyme cleaves its target peptide substrate with a Vmax of 275 mM min-1. The Km for its peptide substrate is 0.07 mM. The K; for the competitive inhibitor Nelfinavir of SARS-Cov is 4.73 mm. Calculate the inhibitor concentration that would lead to an apparent Km (Km,app) of 0.264 mM. Give your answers in units of mM to 1 decimal place.