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The radioactive ions 68Ga³+ (half-life = 68 min) and 8⁹Zr4+ (half-life = 78 hours) are both used in positron emission to
Posted: Fri May 06, 2022 7:37 am
by answerhappygod
- The Radioactive Ions 68ga Half Life 68 Min And 8 Zr4 Half Life 78 Hours Are Both Used In Positron Emission To 1 (161.63 KiB) Viewed 39 times
The radioactive ions 68Ga³+ (half-life = 68 min) and 8⁹Zr4+ (half-life = 78 hours) are both used in positron emission tomography (PET). (a) Give a balanced equation to illustrate the positron decay of 68 Ga³+. (2 marks) (b) Molecular radiopharmaceuticals incorporating 68Ga³+ and 8⁹Zr4+ require multidentate chelators. Compare and contrast the coordination requirements of 68Ga³+ and 8⁹Zr¹+ in terms of: (i) d electron count (ii) coordination number (iii) half-life (iv) ligand preferences (8 marks) (c) Provide an explanation why molecular radiopharmaceuticals incorporating 68Ga³+ are typically based on peptides, while those of 8⁹Zr4+ are based on proteins and antibodies. (2 marks)