Answer Happy

Briefly describe the major signs and symptoms of an under secretion and an over-secretion of thyroid hormone. Understand the reason for the use of T4 over 13 in thyroid hormone replacement therapy • Briefly describe Grave's disease and goitre • Briefly describe the rationale for the use of thionamides. tadioladine and bets blockers for hyperthyroidism, and their major drawbacks or adverse effects. • Very briefly outline the mechanism of action of thionamides, • List the effects of insulin and of glucagon. • Outline briefly the two types of diabetes and their control . Describe the long term effects of a poorly controlled blood glucose level, and the indicators of long term blood glucose control • Understand the pharmacokinetic issues which affect the administration of replacement insulin outline the actions and major adverse effects or drawbacks of the following oral hypoglycaenie druge Metformin, the sulphonylureas the glitazones, the maghicinsidios ano . List the therapeutic and unwanted effects of the glucocorticoide, and their clinical use • Describe the mechanism of action, therapeutic use and adverse effects of the bisphosphonates • Apply your knowledge of the above to cases involving the therapeutic use of these drugs acarbose