Define the term pharmacokinetics and identify which drug characteristics are pharmacokinetic characteristics. Describe,

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Define The Term Pharmacokinetics And Identify Which Drug Characteristics Are Pharmacokinetic Characteristics Describe 1 (40.26 KiB) Viewed 164 times

Define the term pharmacokinetics and identify which drug characteristics are pharmacokinetic characteristics. Describe, in general terms, the advantages and disadvantages of the major enteral and parenteral routes of administration. Be able to predict, in general terms, how the absorption of a drug is affected by the route of administration. Understand the physicochemical characteristics of a drug that will affect the distribution of a drug. Describe the relationship between lonisation of a drug and tes distribution, and between the pH of an environment and the degree of lonisation of a weak acid or alkali Describe the effect of plasma protein binding on drug distribution Describe (briefly the two stages of metabolism and their purpose (detalled chemistry not required) Understand the types of drug interactions that can affect drug metabolism and drug action and the effects these will have on a person's response to a drug List the factors which will affect rates of excretion of drug metabolites and how this may affect response to a druse Be able to define the following: Volume of distribution, clearance, half-life, therapeutic range and apply knowledge of these measures to clinical scenarios in which they may impact a person's response to a drug Apply your knowledge of the above in the context of the therapeutic use of drugs,