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Learning objectives for this week • Understand the factors which govern bronchiole tone. • Be familiar with the triggering factors for asthma. . Outline the mechanism of action therapeutic and adverse effects of p2 agonists, cholinergic antagonists, corticosteroids, sodium cromoglycate, nedocromil sodium • Explain the difference between the drugs used to treat asthma attacks and those used as maintenance treatment. leukotriene antagonists and omalizumab, in connection with respiratory disease • Apply your knowledge of the above to cases involving the therapeutice of these drugs . Briefly describe the disease process and main causes of COPD. • Outline the pharmacological treatment available to como sufferers, and the basis for the use of these treatments