• Understand in broad terms, the major needs for anti-inflammatory medication • Outline the process of inflammation and

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Understand In Broad Terms The Major Needs For Anti Inflammatory Medication Outline The Process Of Inflammation And 1 (39.96 KiB) Viewed 219 times

• Understand in broad terms, the major needs for anti-inflammatory medication • Outline the process of inflammation and how it can change from a protective process to a damaging one. • Describe the mechanism of action of the NSAIDs, both the non-selective and the COX-2 selective. • Outline briefly how and why the non-selective Cox inhibitors produce different effects from the selective cox inhibitors • List the major therapeutic and adverse effects of the non-selective and selective Cox inhibitors. • Outline how paracetamol differs from NSAIDs in its actions, and understand the potential of this drug to cause liver damage. • Recognise the generic names of the following drugs as non selective NSAIDs. Aspirin, the-profens (eg. ibuprofen, ketoprofen, carprofen) • Recognise the generic names of the following drugs as semi selective NSAIDs: the-oxicams (eg. meloxicam, piroxicam), diclofenac • Recognise the generic names for steroidal anti-inflammatory drugs from their -isone, isolone, -asone endings . • Understand the mechanism of action of the steroidal anti-inflammatory drugs, and their therapeutic uses. • List the major adverse effects of these drugs, and be able to relate the route of administration to the most likely side effects. • Outline the mechanism of action and adverse effects of methotrexate eflunomide anakinta, Infliximab, abatacept and sulpha salazine • Apply your knowledge of the above to cases involving the therapeutic use of these drugs