B. Use Table 1 to explicit the so-called enthalpy entropy compensation
Posted: Wed May 04, 2022 3:22 pm
B. Use Table 1 to explicit the so-called enthalpy entropy
compensation
Table 1 Thermodynamic Parameters of Ligand Binding to the ß- Adrenergic Receptor of Turkey Erythrocytes and Ratio of Equilibrium Constants KD at 0 °C and 37 °C AG (kJ/mol) AH (kJ/mol) AS (J/mol deg) TAS (kJ/mol) KD (37 C)/ Kp (0 °C) AGONISTS (-)-isoproterenol -39.3 -56.0 -54.0 -16.7 23 (-)-norephedrine -33.1 <-78.9 - 147.7 <-45.8 55 PARTIAL AGONISTS soteronol -34.4 -32.8 +5.3 +1.6 5.3 fenoterol -32.7 -25.4 +23.6 +7.3 3.6 terbutaline -25.9 -17.3 +27.8 +8.6 2.4 ANTAGONISTS (-)-propranolol -52.3 -16.1 +116.7 +36.2 2.6 IPS-339 <<-51.5 +1.1 +169.5 +52.5 0.95 pindolol -49.6 -21.3 +91.2 +28.3 3.0 sotalol -34.4 -9.0 +81.6 +25.3 1.6 atenolol -31.3 <<-14.5 +54.4 +16.9 2.1 practolol -31.2 +164 +153.6 +47.6 0.45 12
compensation
- B Use Table 1 To Explicit The So Called Enthalpy Entropy Compensation 1 (37.84 KiB) Viewed 44 times