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Inflammation 1. a. Explain why a cast placed around a fractured leg in which extensive tissue damage has occurred might be too tight after 24 hours. b. Explain why such a cast might become loose in 3 weeks. 2. List specific reasons why the inflammatory response is considered a body defense mechanism. 3. a. Explain the rationale for each of the following with acute inflammation: (i) warmth, (ii) fever. b. State three systemic signs of inflammation. 4. Explain why leukocytosis, a differential count, and elevated ESR are useful data but are of limited value. 5. a. Explain how acute inflammation predisposes to the development of infection. b. Classify each as inflammation or infection: (i) sunburn, (ii) skin rash under adhesive tape, (iii) common cold, (iv) red, swollen eye with purulent exudate. 6. How does the presence of thick, cloudy, yellowish fluid in the peritoneal cavity differ from the normal state? 7. If a large volume of fluid has shifted from the blood into the peritoneal cavity, how would this affect blood volume and hematocri2