A patient was admitted to the hospital because of severe hypertension. The patient's acute condition was treated, and th
Posted: Thu Sep 16, 2021 6:02 am
A patient was admitted to the hospital because of severe hypertension. The patient's acute condition was treated, and the physician decided to start the patient on an IV regimen of a new antihypertensive drug, FAE01, that has a therapeutic range of 15-45 mg/L and is completely eliminated by the kidney. Note: After a single IV bolus dose of 450 mg of FAE01 to this patient, a plot of plasma concentration-time profile was linear on a semi-log graph paper. The y intercept of the plot was 30 mg/L and the slope of the line was -0.05 hr-1.
f. What is your recommended dosing regimen to keep FAE01's plasma level within its therapeutic range, taking into consideration the patient's new conditions?
f. What is your recommended dosing regimen to keep FAE01's plasma level within its therapeutic range, taking into consideration the patient's new conditions?