Molecular analysis of the neoplastic cells shows a TP53 gene (tumor suppressor gene) mutation. Which of the following me
Posted: Mon May 02, 2022 8:24 pm
Molecular analysis of the neoplastic cells shows a TP53 gene
(tumor suppressor gene) mutation. Which of the following mechanisms
has most likely produced the neoplastic transformation?
a. Growth factor receptor activation
b. loss of DNA and cell cycle arrest
c. Transcriptional activation
d. induction if angiogenesis
A 32-year-old man who is suffering from glucose-6-phosphate
dehydrogenase deficiency (G6PDD). If he gets married with a normal
homozygous woman, what is the chance of his son having G6PDD?
A 28-year-old man who is suffering from Angelman syndrome. If he
gets married to a woman without any Prada-Willi syndrome or
Angelman syndrome, what is the chance of his offspring having
Angelman syndrome?
Which of the following hypersensitivity disorders only acts on
the membrane-bound antigens?
Type I, Immediate hypersensitivity disorder
Type II, antibody-mediated disorders
Type III, Immune complex–mediated disorder
Type IVb: Delayed-type hypersensitivity
Which of the followings is the negative selection method in
T-cell central tolerance?
a. T cells that display the host’s MHC antigen
and T-cell receptors for a nonself-antigen are allowed to mature in
the thymus
b. T cells that have a high affinity for host
cells are sorted out and undergo apoptosis or cell
death
c. The host antigens are sequestered from the
self-reactive T cells
d. Absence of the costimulatory signals for the
self-reactive T cells
Which of the followings will be resulted in the expansion of
fluids in the interstitial and vascular compartments of
extracellular fluid (ECF)?
a. Isotonic fluid deficient in ECF
compartment
b. Isotonic fluid excess in ECF compartment
c. Hyponatremia
d. Hypernatremia
A 16-year-old boy sustained blunt trauma to his abdomen when
he struck a bridge abutment at high speed while driving a motor
vehicle. Peritoneal lavage shows a hemoperitoneum (presence of
blood in the peritoneal cavity), and at laparotomy, a small portion
of the left lobe of the injured liver is removed. Two months later,
a CT scan of the abdomen shows that the liver has nearly regained
its size before the injury. Which of the following processes best
explains this CT scan finding?
a. Hypertrophy
b. Hyperplasia
c. Dysplasia
d. Metaplasia
Possible cause of edema includes following, EXCEPT:
a. Liver cirrhosis
b. Liver portal vein obstruction
c. Diabetes insipidus
d. Extensive burns
Which of the followings can increase our appetite?
a. Increase in blood glucose
b. Increase in blood ketoacid
c. Decrease in blood Ghrelin
d. Decrease in blood leptin
(tumor suppressor gene) mutation. Which of the following mechanisms
has most likely produced the neoplastic transformation?
a. Growth factor receptor activation
b. loss of DNA and cell cycle arrest
c. Transcriptional activation
d. induction if angiogenesis
A 32-year-old man who is suffering from glucose-6-phosphate
dehydrogenase deficiency (G6PDD). If he gets married with a normal
homozygous woman, what is the chance of his son having G6PDD?
A 28-year-old man who is suffering from Angelman syndrome. If he
gets married to a woman without any Prada-Willi syndrome or
Angelman syndrome, what is the chance of his offspring having
Angelman syndrome?
Which of the following hypersensitivity disorders only acts on
the membrane-bound antigens?
Type I, Immediate hypersensitivity disorder
Type II, antibody-mediated disorders
Type III, Immune complex–mediated disorder
Type IVb: Delayed-type hypersensitivity
Which of the followings is the negative selection method in
T-cell central tolerance?
a. T cells that display the host’s MHC antigen
and T-cell receptors for a nonself-antigen are allowed to mature in
the thymus
b. T cells that have a high affinity for host
cells are sorted out and undergo apoptosis or cell
death
c. The host antigens are sequestered from the
self-reactive T cells
d. Absence of the costimulatory signals for the
self-reactive T cells
Which of the followings will be resulted in the expansion of
fluids in the interstitial and vascular compartments of
extracellular fluid (ECF)?
a. Isotonic fluid deficient in ECF
compartment
b. Isotonic fluid excess in ECF compartment
c. Hyponatremia
d. Hypernatremia
A 16-year-old boy sustained blunt trauma to his abdomen when
he struck a bridge abutment at high speed while driving a motor
vehicle. Peritoneal lavage shows a hemoperitoneum (presence of
blood in the peritoneal cavity), and at laparotomy, a small portion
of the left lobe of the injured liver is removed. Two months later,
a CT scan of the abdomen shows that the liver has nearly regained
its size before the injury. Which of the following processes best
explains this CT scan finding?
a. Hypertrophy
b. Hyperplasia
c. Dysplasia
d. Metaplasia
Possible cause of edema includes following, EXCEPT:
a. Liver cirrhosis
b. Liver portal vein obstruction
c. Diabetes insipidus
d. Extensive burns
Which of the followings can increase our appetite?
a. Increase in blood glucose
b. Increase in blood ketoacid
c. Decrease in blood Ghrelin
d. Decrease in blood leptin