Chorismic acid is a very important branchpoint compound in the shikimic acid pathway. ÇOCH СОН PEP M N HO OH Step1 Step2
Posted: Mon May 02, 2022 7:45 pm
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Chorismic acid is a very important branchpoint compound in the shikimic acid pathway. ÇOCH СОН PEP M N HO OH Step1 Step2 Step3 Step4 OH OH Chorismic acid Shikimic acid (a) To which family does the enzyme that catalyses the first reaction step belong? Which cofactor is involved? (5) (b) Draw the structure of phosphoenolpyruvate (PEP) including ALL atoms and bonds. (5) (c) Draw the structure of glyphosate and explain why it is an inhibitor of the second step of the reaction (15) (d) Give a mechanism and discuss the reactions involved in the conversion of shikimic acid to chorismic acid. (20) (e) Give a possible explanation why the enzyme involved in the last step requires reduced flavin mononucleotide (FMNH) as cofactor. (5)