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Question 1 1 pts Which one of the following statements regarding G-protein-coupled receptors is correct O Binding of the agonist can activate the cytosolic enzymatic activity of the receptor. O They have integral ion channels, therefore modulate the permeability of ions across the cell membrane. O The agonist binds to the extracellular domain of a receptor consisting of 7 transmembrane segments. O Binding of the agonist to the receptor causes the active drug-receptor complex to enter the nucleus. Question 2 1 pts Which one of the following statements about partial agonists is correct? O The maximal agonist effect of a partial agonist is the same as for a full agonist acting at the same receptor. O The potency of a partial agonist is lower than a full agonist acting at the same receptor. The maximum response to a partial agonist occurs at higher levels of receptor occupancy than a full agonist. O The affinity of a partial agonist is lower than a full agonist acting at the same receptor.