Ibuprofen is available in number of different formulations to manage pain. Consider the absorption of the drug from foll

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Ibuprofen Is Available In Number Of Different Formulations To Manage Pain Consider The Absorption Of The Drug From Foll 1 (68.12 KiB) Viewed 60 times

Ibuprofen is available in number of different formulations to manage pain. Consider the absorption of the drug from following Ibuprofen formulations. NurofenTM 12 hour relief 300mg tablets I Nurofen" for children 100mg/5ml. oral suspension NurofenTM for children 100mg chewable capsules Nurofen M 5% topical gel 1. Which of the above formulations would you recommend to a child (2 years of age: weight 11kg) with a fever who has no other medical conditions or allergies. Provide a justification for your choice of recommendation. (4 marks) 2. Using Brufen" tablets as an example formulation, explain the role of excipients in medicines. Your answer should outline the role of each excipient used in the preparation Brufen. (5 marks) 3. Consider the following two brands of ibuprofen: Advil 12 hour extended release tablets and Bruten tablets. Both products contain 400mg of ibuprofen. Explain whether these two products are interchangeable. Your answer should explain how bioequivalence is demonstrated in Australia. (6 marks) 4. Using Advil 12 hour extended release tablets (400mg) TM as an example, explain how excipients can affect the rate of drug release from a formulation. (5 marks)