Section 4 - Evaluate metabolic pathways of your own drug molecules The following tasks refer to your chosen pharmacologi
Posted: Fri Apr 29, 2022 1:39 pm
Section 4 - Evaluate metabolic pathways of your own drug molecules The following tasks refer to your chosen pharmacological class Perform structural analysis to identify functional groups of your drug molecules that are sensitive for oxidation, reduction and/or hydrolysis during Phase 1 metabolism According to functional group analysis predict if your drugs may undergo conjugation with glucuronide, sulfate, amino acid, gluthatione, methylation or acetylation during Phase 2 metabolism. Results of Analysis (in tables) INTERPRETATION OF FINDINGS (Justify your findings by writing a summary of 200 - 250 words in WORDS). CH3 OH H3C -CH3 CH, CH OH Loratadine (Claritin) Fexofenadine (Allegra®) Terfenadine (Seldane®) 4 ОН 3 H 07 ਉ 2 0 1 4 ਨਿਖਤੀ OH H3C Cetirizine (Zyrtec) Desloratadin (Aerius ®) Acrivastin (Semprex-DⓇ)