A 19-year-old woman has severe refractory pustular acne that has been unresponsive to several topical and systemic therapies Treatment with daily oral isotretinoin is begun. Which of the following pharmacologic effects of this drug is dependent on its binding to the RXR receptor?
A. Decreased Propionibacterium acnes proliferation
B. Decreased wax formation
C. Maturation of oocyte follicles
D. Teratogenic effects in the embryo
E. Trafficking of neutrophils through endothelial tight j unctions
A 19-year-old woman has severe refractory pustular acne that has been unresponsive to several topical and systemic thera
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