1. Which of the following describes how opioid analgesics relieve pain? a. Decrease pain nerves impulses from the

[answerhappygod]

1. Which of the following describes how opioid
analgesics relieve pain?
a. Decrease pain nerves impulses from the site of
injury to the brain
b. Decrease production of prostaglandins by
inhibiting cyclooxygenase (COX)
c. Inhibit production and transmission of
substance P
d. Decrease the brain’s ability to sense and
interpret pain
2. Overdose of aspirin and other salicylates may
result in which of the following, especially in children?
a. Gastric distress
b. Liver failure
c. Coma and respiratory failure
d. Renal failure
3. Which of the following are symptoms of acute
opioid overdose or toxicity?
a. Pupil dilation, hypertension, urinary
retention
b. CNS stimulation, hypertension,
tachycardia
c. Pupil constriction, respiratory depression,
hypotension, coma
d. Hyperglycemia, hypotension, bradycardia
4. Which of the following is a partial agonist
opioid analgesic?
a. buprenorphine
b. morphine
c. fentanyl
d. midazolam
5. Sumatriptan and rizatriptan are drugs used
to treat which of the following painful disorders?
a. Migraine headaches
b. Post-herpetic pain
c. Menstrual cramps
d. Burning, stabbing pain
6. Long-term use of aspirin and non-steroidal
anti-inflammatory agents (NSAIDs) may cause which of the following
side effects?
a. Gastric ulcers and GI bleeding
b. Confusion & delirium
c. Constipation and urinary retention
d. All of the above
7. Tom’s dentist prescribed Vicodin (hydrocodone
5 mg + acetaminophen 325mg) 2 tablets every four hours for 48 hours
after a tooth extraction. How should the pharmacist counsel
Tom about his prescription?
a. It may cause constipation and drowsiness
b. Do not drink alcohol while taking this
medication because it may increase drowsiness and sedation
c. This dose of acetaminophen combined with
alcohol may cause liver toxicity
d. All of the above
8. Which of the following correctly defines
tolerance?
a. With prolonged use, increasingly higher doses
are required to produce the same effect
b. With prolonged use, abrupt discontinuation of
the drug produces uncomfortable symptoms
c. Drug craving so intense that normal daily
activities become all about obtaining and taking the drug
d. Compulsive drug seeking and use, despite
harmful consequences
9. Which of the following seizure types is
characterized by an abrupt loss of consciousness, falling, with
extension of trunk and extremities, followed by alternating
contractions and relaxation of the muscles.
a. absence
b. tonic-clonic
c. psychomotor
d. atypical
10. A disadvantage of the first-generation AEDs
is that they have many drug interactions. Which of the following
AEDs do NOT have any significant drug interactions?
a. Gabapentin
b. Levetiracepam (Keppra)
c. Topiramate
d. All of the above
11. Which of the following AEDs is a
broad-spectrum AED (meaning it can be used for several types of
seizures) and has several different MOA?
a. clonazepam
b. valproic acid
c. ethosuximide
d. carbamazepine
12. Status epilepticus (a tonic-clonic seizure
lasting more than 5 minutes) is an emergency situation and can be
life threatening. What is the treatment of choice for this
condition?
a. Valproic acid IV and Lamotrigine IV
b. Lamotrigine IV and clonazepam IV
c. Phenytoin IV (or Fosphenytoin) and IV
lorazepam
d. Carbamazepine IV and Divalproex IV
13. Which of the following is the
recommended treatment for infants that have recently had a febrile
seizure?
a. IV lorazepam
b. rectal diazepam gel
c. IV loading with phenytoin
d. identifcation of and treatment of the cause of
the fever
14. Carbamazepine has many drug interactions and
the following food interaction.
a. Grapefruit juice
b. milk
c. chocolate
d. tree nuts
15. Which of the following medications is an antidepressant that
inhibits the reuptake of both serotonin and
norepinephrine?
e. Fluoxetine
f. isocarboxazid
g. venlafaxine
h. citalopram
16. Which of the following antipsychotic
medications may cause extrapyramidal side effects because it blocks
dopamine receptors and unbalances cholinergic activities?

a. chlorpromazine
b. risperidone
c. aripiprazole
d. ziprasidone
17. The atypical antipsychotics such as
quetiapine (Seroquel) are associated with which of the following
adverse effects?
a. Weight gain and Type 2 DM
b. Shuffling walk & tardive dyskinesia
c. Kidney dysfunction
d. Chronic dry cough
18. After taking promethazine both orally and
rectally for vomiting, Janet was unable to speak normally due to
muscle spasms in her neck and face and thrusting of her tongue.
What is this reaction called?
a. Status epilepticus
b. Tardive dyskinesia
c. Acute dystonic reaction
d. Petit mal seizure
19. Andie is taking the MAO-I antidepressant
phenelzine and has been told that there are a number of foods such
as aged cheese and cured meats and herbal preparations she must
avoid because of potentially dangerous side effects. What reaction
may occur if these foods are combined with phenelzine?
a. Hypertensive crisis
b. Atrial fibrillation
c. Ventricular fibrillation
d. Liver failure
20. Which of the following medications is
effective in treating bipolar disorder and has been shown to reduce
suicide rates in these patients?
a. carbamazepine
b. valproate
c. lithium
d. olanzapine