Carefully study the following transformation and answer the questions that follow OH TBSO tBuOOH, (-)-DET, TI(O'Pr)4 CH₂
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Carefully study the following transformation and answer the questions that follow OH TBSO tBuOOH, (-)-DET, TI(O'Pr)4 CH₂
questions that follow OH TBSO tBuOOH, (-)-DET, TI(O'Pr)4 CH₂Cl₂, -23 °C, 77%, 100% ee 3.1 Give the product of the above reaction, showing the correct stereochemistry. (2) 3.2 How do you account for the stereochemistry of the product? Please explain and mention what you would do to get the product with the opposite stereochemistry. (4) 3.3 What is the difference between kinetic resolution and reagent controlled asymmetric synthesis? Please explain in detail, giving an example of each. 8)
Carefully study the following transformation and answer the