Mar A 19 year-old student who is studying for final exams has not eaten for nearly two days. As a result, transcription

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Mar A 19 Year Old Student Who Is Studying For Final Exams Has Not Eaten For Nearly Two Days As A Result Transcription 1 (41.19 KiB) Viewed 13 times

Mar A 19 year-old student who is studying for final exams has not eaten for nearly two days. As a result, transcription of the PEP carboxykinase (PEPCK) gene is induced in his liver cells in response to low blood glucose. Which of the following pathways is involved in this activation of gene expression? Scratch out (A) Scratch out (B) Glucocorticoids bind to glucocorticoid receptors (GRs) on the cell surface, resulting in internalization of GRs and their subsequent nuclear transport. Glucagon stimulates increased cAMP levels and nuclear translocation of the catalytic subunit of PKA, which then phosphorylates CREB/CREBP. DNA-bound glucocorticoid receptors recruit histone deacetylases upon hormone binding. Increased intracellular levels of cAMP result in nuclear translocation of PKA and its subsequent binding to DNA. Scratch out (C) Scratch out (D)