1.2 Suppose that we want to evaluate the role of intravenous pulse cyclophosphamide (IVCP) infusion in the management of

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1 2 Suppose That We Want To Evaluate The Role Of Intravenous Pulse Cyclophosphamide Ivcp Infusion In The Management Of 1 (57.26 KiB) Viewed 39 times

1.2 Suppose that we want to evaluate the role of intravenous pulse cyclophosphamide (IVCP) infusion in the management of nephrotic syndrome in children with steroid Page 1 of 3 resistance. Children were given a monthly infusion of IVCP in a dose of 500 to 700 a mg/m2. The following data represent levels of serum albumin (g/dL) before and after IVCP in 14 randomly selected children with nephrotic syndrome. Pre-IVCP Post-IVCP Pre - Post 22.5 1.5 3.5 4.34 -1.5 -1.8-2.5 22.3 2.1 2.3 1 2.2 1.8 2 2 1.5 3.4 43.8 2.4 3.5 1.7 3.8 3.6 3.8 3.8 4.1 3.4 -2 -1.5 -0.3 -1.2-0.7 -1.6 -1.8 -1.8 -1.8 -2.6 0 Assuming that the difference of each pair is approximately normal, test that mean Pre-IVCP is less than the Post-IVCP at a = 0.05. [10]

QUESTION THREE (25 Marks] An agricultural scientist plants Lucerne on several identical plots of land except for the soil pH. Following are the dry matter harvest (in kilograms per hectares) for each plot. pH 4.6 4.8 5.2 5.4 5.6 5.8 6.0 Harvest 1056 1833 1629 1852 1783 2647 2131 a) Fit a simple regression line of harvest on the soil pH. b) Interpret the estimated coefficients c) Determine the coefficient of determination and discuss what this tells you. d) Conduct a test to determine whether the pH and the harvest are linearly related. e) Is the fit of a simple linear model good enough to allow the scientist to predict harvest when the pH is &? If so, find the 95 % prediction interval. If not, explain why not.