The fixation probability for a recessive advantageous mutant (VAA = 1, V A = Vaa = 1 - s) in a population containing N i

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The Fixation Probability For A Recessive Advantageous Mutant Vaa 1 V A Vaa 1 S In A Population Containing N I 1 (42.03 KiB) Viewed 35 times

The fixation probability for a recessive advantageous mutant (VAA = 1, V A = Vaa = 1 - s) in a population containing N individuals is 2s V NA Notice that this probability depends on N no matter how large s is. The fixation probability of a strongly advantageous allele with an additive effect of 0.1% on viability is approximately 2s = 0.002. How large would s have to be for a recessive advantageous allele to have the same fixation probability in a population of 10,000 individuals? [Give your answer to three decimal places.]