B. Rosiglitazone is the active ingredient in the controversial
type 2 diabetes medicine Avandia and has been linked to an
increased risk of serious cardiovascular problems such as stroke,
heart failure, and death. A common alternative treatment is
Pioglitazone, the active ingredient in a diabetes medicine called
Actos. In a nationwide retrospective observational study of 227,571
Medicare beneficiaries aged 65 years or older, it was found that
2,593 of the 67,593 patients using Rosiglitazone and 5,386 of the
159,978 using Pioglitazone had serious cardiovascular problems.
Below is a graph for 100 simulated results for scenario (b)
above.
Why are these simulated results centered around 0?
Based on this graph, give an estimate of the P-value. Explain or
show work.
What would you conclude about the relationship between taking
Rosiglitazone and having cardiovascular problems in diabetic
patients?
(THIS IS ALL THE INFORMATION IN THE PROBLEM)
12 10 8 Count 6 2 0 0.002 -0.001 0.000 0.001 Difference in randomized cardiovascular problem rates (Rosiglitazone - Pioglitazone)
B. Rosiglitazone is the active ingredient in the controversial type 2 diabetes medicine Avandia and has been linked to a
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B. Rosiglitazone is the active ingredient in the controversial type 2 diabetes medicine Avandia and has been linked to a
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